Millions of people around the world suffer from depression, the most common mental disorder of all. Since depression appears to be largely genetic, several long-standing questions continue to bedevil researchers. Have the genes for clinical unipolar depression undergone selective evolution–or is depression a random product of mutation, evolutionary drift, or other non-selective forces?

The symptoms of depression are found in every culture and time period, from the ancient Greeks to modern New Yorkers, from the !Kung of southern Africa to ranchers in the American West. Why is depression so much more common than any other major mental illness? Clearly, it is a malfunction, a maladaptation — or is it? … [visit site to read more]

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