Two Wrongs Make a Right – Abnormal Brain Circuitry May Stop Abnormal Movement

Neuroscience and Neurology CategoryA solution to an abnormal neurological movement problem can perhaps be abnormal as well. The irregular wiring of the brain may actually eliminate dystonia — repetitive movements and atypical postures. According to the Journal of Neuroscience, changes in brain pathways may actually counteract the genetic mutations for the movement disorder. This idea can explain why a few individuals with the inherited mutation are able to live normal lives.

Researchers at the Feinstein Institute identified two specific brain pathways that influence the severity of dystonia symptoms. All individuals who carry the mutations and symptoms for dystonia have an abnormal pathway between the cerebellum and the thalamus, but a normal second pathway between the thalamus and the cortex. … [visit site to read more]

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